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Sterilization
by design 

 

One sterile process, three perspectives: every market has its own products, production environments, regulatory requirements and process challenges.

First select your market and then choose your perspective, because your market defines the perimeter, while the cube will then the technologies, applications and packaging experiences relevant to your manufacturing environment.

Technology
when you already know the type of solution you are looking for.

Application
when you want to understand how we address the specific challenges of your product and manufacturing process.

Packaging
when material, geometry and configuration determine how the load will respond to sterilization.

Select your market
Small Molecules
Biotech
ATMP - genes, tissues or cells
Medical Devices
Primary packaging
OSD
R&D and LAB centers
Cosmetic

TH - our TECHNOLOGY HUB

A common platform for process control, data integrity, cybersecurity, connectivity and lifecycle management across markets, processes and products.

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Select your driver

By application
By technology
By packaging
Select your driver
By application
By technology
By packaging
Biotech

High temperature for solid loads

In biotech and aseptic fill & finish manufacturing, the sterility of machine parts, tools, empty containers, filters, garments and other critical product-contact components directly impacts process integrity and patient safety.
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Small Molecules

High temperature for solid loads

In biotech and aseptic fill & finish manufacturing, the sterility of machine parts, tools, empty containers, filters, garments and other critical product-contact components directly impacts process integrity and patient safety.
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Primary packaging

High temperature for solid loads

In biotech and aseptic fill & finish manufacturing, the sterility of machine parts, tools, empty containers, filters, garments and other critical product-contact components directly impacts process integrity and patient safety.
Discover more
Cosmetic

High temperature for solid loads

In biotech and aseptic fill & finish manufacturing, the sterility of machine parts, tools, empty containers, filters, garments and other critical product-contact components directly impacts process integrity and patient safety.
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Biotech

High Temperature for porous loads

Manufacturing components such as stoppers, filters, garments and silicone tubing requires more than achieving sterility.
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Small Molecules

High Temperature for porous loads

Manufacturing components such as stoppers, filters, garments and silicone tubing requires more than achieving sterility.
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Medical Devices

High Temperature for porous loads

Manufacturing components such as stoppers, filters, garments and silicone tubing requires more than achieving sterility.
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Primary packaging

High Temperature for porous loads

Manufacturing components such as stoppers, filters, garments and silicone tubing requires more than achieving sterility.
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Cosmetic

High Temperature for porous loads

Manufacturing components such as stoppers, filters, garments and silicone tubing requires more than achieving sterility.
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Small Molecules

Terminal sterilization for closed liquids

Small molecules continue to represent a major share of sterile pharmaceutical manufacturing worldwide. For heat-stable formulations, terminal sterilization remains the preferred sterility assurance approach because it allows the final packaged product to be sterilized after filling and closing.
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Medical Devices

Terminal sterilization for closed liquids

Small molecules continue to represent a major share of sterile pharmaceutical manufacturing worldwide. For heat-stable formulations, terminal sterilization remains the preferred sterility assurance approach because it allows the final packaged product to be sterilized after filling and closing.
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Primary packaging

Terminal sterilization for closed liquids

Small molecules continue to represent a major share of sterile pharmaceutical manufacturing worldwide. For heat-stable formulations, terminal sterilization remains the preferred sterility assurance approach because it allows the final packaged product to be sterilized after filling and closing.
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Cosmetic

Terminal sterilization for closed liquids

Small molecules continue to represent a major share of sterile pharmaceutical manufacturing worldwide. For heat-stable formulations, terminal sterilization remains the preferred sterility assurance approach because it allows the final packaged product to be sterilized after filling and closing.
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Biotech

Validated washing

Pharmaceutical parts and components can carry viable microorganisms, particles and chemical residues, including endotoxins. As manufacturers move from operator-dependent manual washing to automated processes, the objective is not simply repeatable execution, but a demonstrated cleaning outcome across all three contamination classes.
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Small Molecules

Validated washing

Pharmaceutical parts and components can carry viable microorganisms, particles and chemical residues, including endotoxins. As manufacturers move from operator-dependent manual washing to automated processes, the objective is not simply repeatable execution, but a demonstrated cleaning outcome across all three contamination classes.
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Primary packaging

Validated washing

Pharmaceutical parts and components can carry viable microorganisms, particles and chemical residues, including endotoxins. As manufacturers move from operator-dependent manual washing to automated processes, the objective is not simply repeatable execution, but a demonstrated cleaning outcome across all three contamination classes.
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OSD

Validated washing

Pharmaceutical parts and components can carry viable microorganisms, particles and chemical residues, including endotoxins. As manufacturers move from operator-dependent manual washing to automated processes, the objective is not simply repeatable execution, but a demonstrated cleaning outcome across all three contamination classes.
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Cosmetic

Validated washing

Pharmaceutical parts and components can carry viable microorganisms, particles and chemical residues, including endotoxins. As manufacturers move from operator-dependent manual washing to automated processes, the objective is not simply repeatable execution, but a demonstrated cleaning outcome across all three contamination classes.
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Biotech

Combined washing and sterilization

In high-potent manufacturing, isolator-based aseptic processing and space-constrained facilities, contamination control extends beyond removing residues from components.
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Small Molecules

Combined washing and sterilization

In high-potent manufacturing, isolator-based aseptic processing and space-constrained facilities, contamination control extends beyond removing residues from components.
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OSD

Combined washing and sterilization

In high-potent manufacturing, isolator-based aseptic processing and space-constrained facilities, contamination control extends beyond removing residues from components.
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Biotech

Low Temperature Sterilization

Many products cannot tolerate the temperatures and humidity associated with moist heat sterilization.
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Small Molecules

Low Temperature Sterilization

Many products cannot tolerate the temperatures and humidity associated with moist heat sterilization.
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Medical Devices

Low Temperature Sterilization

Many products cannot tolerate the temperatures and humidity associated with moist heat sterilization.
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Primary Packaging

Low Temperature Sterilization

Many products cannot tolerate the temperatures and humidity associated with moist heat sterilization.
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Biotech

Combined sterilization and decontamination

Modern pharmaceutical facilities must support an increasing variety of materials, production scenarios and transfer requirements. This demands access to both sterilization and surface decontamination: two distinct processes serving different treatment needs.
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Small Molecules

Combined sterilization and decontamination

In high-potent manufacturing, isolator-based aseptic processing and space-constrained facilities, contamination control extends beyond removing residues from components. Materials often need to move between classified environments while preserving the conditions required for safe transfer.
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Primary packaging

Combined sterilization and decontamination

Modern pharmaceutical facilities must support an increasing variety of materials, production scenarios and transfer requirements. This demands access to both sterilization and surface decontamination: two distinct processes serving different treatment needs.
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Biotech

Decontamination

Every material entering an aseptic environment creates a potential contamination pathway. Even when the content is sterile, external surfaces may have been exposed during handling, storage and transportation.
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Small Molecules

Decontamination

Every material entering an aseptic environment creates a potential contamination pathway. Even when the content is sterile, external surfaces may have been exposed during handling, storage and transportation.
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Biotech

Automated handling

In high-capacity terminal sterilization lines, production continuity depends on much more than sterilizer performance. Products must be accumulated, configured, loaded, processed, unloaded and transferred downstream without interrupting the production flow.
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Small Molecules

Automated handling

In high-capacity terminal sterilization lines, production continuity depends on much more than sterilizer performance. Products must be accumulated, configured, loaded, processed, unloaded and transferred downstream without interrupting the production flow.
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Medical Devices

Automated handling

In high-capacity terminal sterilization lines, production continuity depends on much more than sterilizer performance. Products must be accumulated, configured, loaded, processed, unloaded and transferred downstream without interrupting the production flow.
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Primary Packaging

Automated handling

In high-capacity terminal sterilization lines, production continuity depends on much more than sterilizer performance. Products must be accumulated, configured, loaded, processed, unloaded and transferred downstream without interrupting the production flow.
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Biotech

Dry-heat depyrogenation

Sterile manufacturing must control microorganisms, bacterial endotoxins and particles. Sterilization addresses viable contamination but does not necessarily eliminate endotoxins and pyrogens from glassware and product-contact components entering aseptic production.
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Small Molecules

Dry-heat depyrogenation

Sterile manufacturing must control microorganisms, bacterial endotoxins and particles. Sterilization addresses viable contamination but does not necessarily eliminate endotoxins and pyrogens from glassware and product-contact components entering aseptic production.
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OSD

Dry-heat depyrogenation

Sterile manufacturing must control microorganisms, bacterial endotoxins and particles. Sterilization addresses viable contamination but does not necessarily eliminate endotoxins and pyrogens from glassware and product-contact components entering aseptic production.
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ATMP - genes, tissues or cells

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
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Biotech

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
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Small Molecules

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
Medical Devices

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
Primary packaging

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
OSD

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
R&D and LAB centers

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
Cosmetic

Sterility test isolation

A positive sterility test can place an entire batch on hold. But when contamination originates from the testing environment, the result triggers investigations, retesting and release delays without revealing a manufacturing failure.
Discover more
Biotech

Stopper Treatment

As aseptic filling lines become faster and batch values increase, the transfer of elastomeric closures becomes a critical step in contamination control.
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Small Molecules

Stopper Treatment

As aseptic filling lines become faster and batch values increase, the transfer of elastomeric closures becomes a critical step in contamination control.
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Primary packaging

Stopper Treatment

As aseptic filling lines become faster and batch values increase, the transfer of elastomeric closures becomes a critical step in contamination control.
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ATMP - genes, tissues or cells

GMP robotic ATMP factory

ATMP manufacturing still relies on highly trained operators to connect systems, load instruments, transfer materials and coordinate operations across fragmented process equipment. Every connection, transfer and movement creates another opportunity for contamination, variability, delay or manufacturing failure.
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R&D and LAB centers

GMP robotic ATMP factory

ATMP manufacturing still relies on highly trained operators to connect systems, load instruments, transfer materials and coordinate operations across fragmented process equipment. Every connection, transfer and movement creates another opportunity for contamination, variability, delay or manufacturing failure.
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ATMP - genes, tissues or cells

Configurable high-temperature sterilization

In pharmaceutical R&D and Quality Control, sterilization requirements evolve with formulations, containers, materials and test methods. The same laboratory may need to process culture media, porous solids, open liquids and closed or deformable containers: each responding differently to heat, pressure, steam and cooling.
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R&D and LAB centers

Configurable high-temperature sterilization

In pharmaceutical R&D and Quality Control, sterilization requirements evolve with formulations, containers, materials and test methods. The same laboratory may need to process culture media, porous solids, open liquids and closed or deformable containers: each responding differently to heat, pressure, steam and cooling.
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ATMP - genes, tissues or cells

Configurable washing

In pharmaceutical R&D and Quality Control, glassware and instruments support tests, formulations and microbiological activities whose reliability depends on what happens before the work begins.
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R&D and LAB centers

Configurable washing

In pharmaceutical R&D and Quality Control, glassware and instruments support tests, formulations and microbiological activities whose reliability depends on what happens before the work begins.
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ATMP - genes, tissues or cells

Biohazard decontamination

In laboratories handling biologically hazardous materials, microbial inactivation is only part of the challenge.
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R&D and LAB centers

Biohazard decontamination

In laboratories handling biologically hazardous materials, microbial inactivation is only part of the challenge.
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Small Molecules

Solutions for IV bags

IV bags are commonly manufactured in large quantities for the delivery of infusion solutions, electrolytes, nutrients and pharmaceutical formulations.
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Biotech

Solutions for insulin processing

Insulin production increasingly relies on high-throughput syringes and cartridge filling lines, with cartridges serving reusable and disposable delivery pens. At these output levels, filling capacity alone does not determine production performance.
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Biotech

Solutions for vaccines

Vaccine manufacturing places exceptional demands on fill-finish operations, where product sterility depends on the controlled preparation and transfer of every component entering the aseptic filling area.
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R&D and LAB centers

Solutions for vaccines

Vaccine manufacturing places exceptional demands on fill-finish operations, where product sterility depends on the controlled preparation and transfer of every component entering the aseptic filling area.
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Small Molecules

Solutions for high-viscosity products

Hyaluronic acid pre-filled syringes combine a thermally sensitive formulation with a pressure-sensitive container-closure system.
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Cosmetic

Solutions for high-viscosity products

Hyaluronic acid pre-filled syringes combine a thermally sensitive formulation with a pressure-sensitive container-closure system.
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Biotech

Solutions for albumin pasteurization

Albumin is a heat-sensitive biological product. Once prepared, purified, formulated and stabilized, it is sterile-filtered and aseptically filled into final glass vials or bottles.
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Small Molecules

Solutions for radiopharmaceuticals

Radiopharmaceutical production combines pharmaceutical contamination control with the radiological protection of operators and the surrounding environment.
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R&D and LAB centers

Solutions for radiopharmaceuticals

Radiopharmaceutical production combines pharmaceutical contamination control with the radiological protection of operators and the surrounding environment.
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ATMP - genes, tissues or cells

Solutions for CAR-T cell therapy

CAR-T therapies transform a patient’s own immune cells into a personalized treatment, but every individual batch must move through a complex, time-sensitive manufacturing journey.
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R&D and LAB centers

Solutions for CAR-T cell therapy

CAR-T therapies transform a patient’s own immune cells into a personalized treatment, but every individual batch must move through a complex, time-sensitive manufacturing journey.
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OSD

Solutions for sterile powder manufacturing

Sterile powder manufacturing presents one of the most demanding combinations of aseptic processing and high-containment production.
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Cosmetic

Solutions for sterile powder manufacturing

Sterile powder manufacturing presents one of the most demanding combinations of aseptic processing and high-containment production.
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Biotech

High-potent aseptic manufacturing

High-potent sterile manufacturing is one of the fastest-growing pharmaceutical sectors, driven by oncology biologics, antibody-drug conjugates (ADCs), peptides and other highly active compounds.
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OSD

High-potent aseptic manufacturing

High-potent sterile manufacturing is one of the fastest-growing pharmaceutical sectors, driven by oncology biologics, antibody-drug conjugates (ADCs), peptides and other highly active compounds.
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R&D and LAB centers

High-potent aseptic manufacturing

High-potent sterile manufacturing is one of the fastest-growing pharmaceutical sectors, driven by oncology biologics, antibody-drug conjugates (ADCs), peptides and other highly active compounds.
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Cosmetic

High-potent aseptic manufacturing

High-potent sterile manufacturing is one of the fastest-growing pharmaceutical sectors, driven by oncology biologics, antibody-drug conjugates (ADCs), peptides and other highly active compounds.
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Medical Devices

Solutions for contact lenses

Contact lens manufacturing combines high-volume production, delicate ophthalmic products and increasingly sophisticated packaging concepts.
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R&D and LAB centers

Solutions for contact lenses

Contact lens manufacturing combines high-volume production, delicate ophthalmic products and increasingly sophisticated packaging concepts.
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Medical Devices

Solutions for blistered prefilled syringes

Drug-device combination products can bring together a thermosensitive drug, a complex delivery system and a protective package within a single sterilization challenge.
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Medical Devices

Solutions for artificial valves

Artificial valves combine long-term implant performance with exceptional material and geometrical complexity.
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Medical Devices

Solutions for hemodialysis blood tubing set

Hemodialysis blood tubing sets form the extracorporeal connection between the patient and the dialysis system.
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R&D and LAB centers

Solutions for hemodialysis blood tubing set

Hemodialysis blood tubing sets form the extracorporeal connection between the patient and the dialysis system.
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Medical Devices

Solutions for surgical sutures

Packaged surgical sutures combine variables that respond differently to sterilization: absorbable or non-absorbable polymers, braided or monofilament structures, functional coatings and multilayer barrier systems.
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ATMP - genes, tissues or cells

Solutions for RTU vials

Ready-to-fill vial manufacturers supply pharmaceutical companies with primary containers that are already washed, depyrogenated, packaged and sterile, transferring container preparation and part of its qualification burden upstream.
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Biotech

Solutions for RTU vials

Ready-to-fill vial manufacturers supply pharmaceutical companies with primary containers that are already washed, depyrogenated, packaged and sterile, transferring container preparation and part of its qualification burden upstream.
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Medical Devices

Solutions for RTU vials

Ready-to-fill vial manufacturers supply pharmaceutical companies with primary containers that are already washed, depyrogenated, packaged and sterile, transferring container preparation and part of its qualification burden upstream.
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Primary packaging

Solutions for RTU vials

Ready-to-fill vial manufacturers supply pharmaceutical companies with primary containers that are already washed, depyrogenated, packaged and sterile, transferring container preparation and part of its qualification burden upstream.
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ATMP - genes, tissues or cells

Solutions for RTU cartridges or syringes

Ready-to-use cartridge manufacturers are taking on a critical role in biopharmaceutical supply chains
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Biotech

Solutions for RTU cartridges or syringes

Ready-to-use cartridge manufacturers are taking on a critical role in biopharmaceutical supply chains
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Medical Devices

Solutions for RTU cartridges or syringes

Ready-to-use cartridge manufacturers are taking on a critical role in biopharmaceutical supply chains
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Primary packaging

Solutions for RTU cartridges or syringes

Ready-to-use cartridge manufacturers are taking on a critical role in biopharmaceutical supply chains
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ATMP - genes, tissues or cells

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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Biotech

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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Small Molecules

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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Medical Devices

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
Discover more
Primary packaging

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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OSD

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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R&D and LAB centers

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
Discover more
Cosmetic

Aseptic transfer

Aseptic manufacturing depends on preserving the required state of every material until its point of use. Yet reusable parts, pre-sterilized components, bulk closures, tools and auxiliary materials enter the process from different conditions, through different routes and with different vulnerabilities.
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ATMP - genes, tissues or cells

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
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Biotech

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
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Small Molecules

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
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Medical Devices

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
Discover more
Primary packaging

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
Discover more
OSD

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
Discover more
R&D and LAB centers

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
Discover more
Cosmetic

Glass vials

The rapid growth of biologics, nanoparticle-based medicines and Advanced Therapy Medicinal Products (ATMPs) is redefining the relationship between pharmaceutical formulations and primary packaging.
Discover more
ATMP - genes, tissues or cells

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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Biotech

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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Small Molecules

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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Medical Devices

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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Primary packaging

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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OSD

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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R&D and LAB centers

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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Cosmetic

Thermal sterilization of multichamber bags

A multichamber bag enters the sterilization process as a single container, but its chambers do not behave as a single product.
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ATMP - genes, tissues or cells

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
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Biotech

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
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Small Molecules

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
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Medical Devices

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
Discover more
Primary packaging

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
Discover more
OSD

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
Discover more
R&D and LAB centers

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
Discover more
Cosmetic

Steam sterilization of machine parts in Tyvek® bags

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.
Discover more
ATMP - genes, tissues or cells

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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Biotech

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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Small Molecules

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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Medical Devices

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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Primary packaging

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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OSD

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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R&D and LAB centers

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
Discover more
Cosmetic

Blister

A sealed blister changes throughout thermal sterilization. As temperature rises, the liquid expands, part of it may vaporize and the gas in the headspace increases in pressure. The resulting internal pressure acts directly on the blister cavity and its peel seal.
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ATMP - genes, tissues or cells

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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Biotech

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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Small Molecules

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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Medical Devices

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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Primary packaging

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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OSD

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
Discover more
R&D and LAB centers

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
Discover more
Cosmetic

Pre-filled syringes

A pre-filled syringe is a hermetically sealed container with a movable plunger. During thermal sterilization, the liquid expands, part of it vaporizes, dissolved gases are released and the gas already present in the headspace increases in pressure.
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ATMP - genes, tissues or cells

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems.
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Biotech

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
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Small Molecules

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
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Medical Devices

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
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Primary packaging

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
Discover more
OSD

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
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R&D and LAB centers

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems.
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Cosmetic

RTS stoppers

Ready-to-Sterilize (RTS) stoppers are expected to enter aseptic manufacturing immediately after sterilization through Rapid Transfer Port (RTP) systems. This requires every sterilization cycle to deliver stoppers in the same microbiological and physical condition, ensuring repeatable process performance from batch to batch.
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ATMP - genes, tissues or cells

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
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Biotech

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
Small Molecules

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
Medical Devices

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
Primary packaging

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
OSD

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
R&D and LAB centers

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
Cosmetic

Stopper in bulk

Internalizing bulk stopper preparation means directly assuming technical responsibility and controlling all critical quality variables before aseptic filling.
Discover more
ATMP - genes, tissues or cells

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
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Biotech

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
Small Molecules

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
Medical Devices

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
Primary packaging

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
OSD

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
R&D and LAB centers

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
Cosmetic

Sterilization of RTP Canisters for aseptic transfer

In modern aseptic manufacturing, RTP canisters are increasingly used to transfer product-contact parts and filling assemblies into Grade A isolators.
Discover more
ATMP - genes, tissues or cells

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
Biotech

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
Small Molecules

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
Medical Devices

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
Primary packaging

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
OSD

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
R&D and LAB centers

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more
Cosmetic

RTU vials in nest

When manufacturers seek to move away from EtO towards a method that reduces toxic-residue concerns and the potential burden on patients, workers and the environment, selecting an alternative sterilant is only the beginning.
Discover more

THREE PERSPECTIVES, SIX FACES

Deepen your understanding of sterile-process and manufacturing challenges through Fedegari insights, articles and white papers.

WHITE PAPER AND RESEARCH

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A growing collection of white papers and research contributions grounded in real application experience across industries, processes and manufacturing environments..

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Packaging is an active part of the sterilization process. Its materials, geometry, barrier structure, sealing system and load configuration influence process penetration and how integrity must be preserved.

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