Solutions for artificial valves

Deep vacuum for complex, heat-sensitive assemblies.

Vaporized hydrogen peroxide provides a low-temperature route for devices containing heat-sensitive biological, polymeric or textile elements. Deep vacuum improves air removal from cavities, restricted passages, layered structures and non-vented interfaces, supporting controlled sterilant penetration. Injection, exposure, vacuum removal and aeration are configured around the device and packaging, with residual evaluation included in the development strategy.

The automated manipulator connects treatment and point of use through controlled loading, unloading, movement and delivery operations. Depending on the selected route, it handles canisters, sterile tanks or treated materials and manages their interface with the isolator or filling line. Automation removes avoidable manual interventions precisely where exposure, repeated handling and open connections create the greatest vulnerability.

Tyvek® bags provide a sterile barrier while allowing steam penetration, but processing machine parts inside porous packaging — particularly in double-bag configurations — introduces challenges that cannot be managed by temperature alone.

Irregular geometries, different thermal masses, folds, overlapping surfaces and contact with the trays influence air removal, steam circulation and condensate evacuation. At the same time, rapid pressure changes can mechanically stress the bags, while poorly controlled depressurization can cool the load and make drying more difficult.